What are toxins and how do they accumulate in the body?
Any agent (physical, chemical, or microbial) that adversely modifies or damages a balanced biological system is considered a “toxin.”

These physical, chemical, and microbial agents may originate in the body as a by-product of metabolism or may enter from the external environment.
Endogenous toxins: those originating within the body
  • By-products of physiological metabolism, such as
    • Ammonia
    • Bilirubin
    • Creatinine
    • Lactic acid
    • Uric acid
  • Metabolites under abnormal metabolic conditions, such as
    • Normal waste products abnormally accumulating, like CO2, H20
    • Microbial breakdown products
    • Excess production of neurotransmitters or hormones
    • Excess degradation of neurotransmitters or hormones
    • Excess free radical formation
  • Toxins acquired from the environment and stored in tissues, which then are continuously released, such as
    • Dental materials
    • Medical implants
    • Unresolved Microbial foci
Exogenous toxins: those originating from the external environment, also known as xenobiotics
  • Ingested and absorbed through the gastro-intestinal system, including:
    • toxic metals
    • industrial chemicals
    • hormones and drugs in animal food
    • food additives
    • fertilizers
    • pesticides
    • microbes
    • mycotoxins
  • Inhaled through the respiratory system, including
    • outdoor air pollution from natural or man-made chemicals
    • indoor pollutants from:
      • building materials
      • household products
      • pets
      • dust
      • mold
      • microbes
  • Absorbed through the skin, especially through
    • bathing
    • the air
    • cosmetics and lotions
  • Injected into the skin, such as
    • insect bites
    • prescription drugs
    • recreational drugs
What are the effects of toxins on the body?

Paracelsus is known for his saying that the dose makes the poison. All toxins can damage or adversely modify a biological system in their relevant dose. The effects of toxins on the body are dependent on the actual substance, its organotropism, concentration, and the rate of exposure of the toxin as well as the capacity of the body to eliminate.

More importantly, the effect is dependent of the state of health of the body. This is where the total toxic load and the ability of the cells and organs to detoxify comes into play. This is determined by the miasm, or reactional mode of the individual.

Toxins accumulate when there is an excess of production in relation to the amount processed by the individual cells, routed to the organs of detoxification and excreted.

Introduction to Bioregulatory Medicine
Alta Smit, Arturo O’Byrne, Bruno Van Brandt, Ivo Bianchi, Klaus Kuestermann, 2009 Georg Thieme Verlag, Stuttgart, Germany